Multiple clustered dermatofibroma associated with asymptomatic pericardial cyst
Abstract
Multiple clustered dermatofibroma (MCDF) is an unusual variant of dermatofibroma (DF) presentation, localized on one segment of the body. Multiple dermatofibroma is a term for when there are more than 15 dermatofibromas, which in itself is already a rare condition. The dermatofibromas usually appear in younger adults and are predominantly located on lower parts of the body. No associations, except one case with pulmonary hypertension, were described in patients with MCDF. Herein we present another case of this rare complaint in a 58 year old female with clustered lesions on the thigh. Pericardial cyst was identified in our patient during routine chest X-ray and the patient is asymptomatic. MCDFs do not usually require treatment unless requested by the patient for cosmetic reason. This variant of MCDF, which is neither congenital nor eruptive, is extraordinarily rare, with only 13 cases reported. Further reports may identify possible associations of MCDF.
References
Bhabha FK, Magee J, Ng SY, Grills CE, Su J, et al. Multiple clustered dermatofibroma presenting in a segmental distribution. Australas J Dermatol 2016; 57(1): e20–e22. doi: 10.1111/ajd.12257
Evans J, Mattacks CA, Clarke T, Pond CM. Dermatofibromas and arthropod bites: Is there any evidence to link the two? Lancet 1989; 334(8653): 36–37. doi: 10.1016/S0140-6736(89)90267-5.
Huang PY, Chu CY, Hsiao CH. Multiple eruptive dermatofibromas in a patient with dermatomyositis taking prednisolone and methotrexate. J Am Acad Dermatol 2007; 57(5): 81–84. doi: 10.1016/j.jaad.2006.05.070
Gualandri L, Betti R, Cerri A, Pazzini C, Crosti C. Eruptive dermatofibromas and immunosuppression. Eur J Dermatol 1999; 9(1): 45–47.
Ammirati CT, Mann C, Hornstra IK. Multiple eruptive dermatofibromas in three men with HIV infection. Dermatology 1997; 195(4): 344–348.
Bachmeyer C, Cordier F, Blum L, Cazier A, Vérola O, et al. Multiple eruptive dermatofibromas after highly active antiretroviral therapy. Br J Dermatol. 2000; 143(6): 1336–1337. doi: 10.1046/j.1365-2133.2000.03924.x.
Pinto-Almeida T, Caetano M, Alves R, Selores M. Congenital multiple clustered dermatofibroma and multiple eruptive dermatofibromas-Unusual presentations of a common entity. An Bras Dermatol 2013; 88(6 Suppl 1): 63–66. doi: 10.1590/abd1806-4841.20132647.
Finch J, Berke A, McCusker M, Chang MW. Congenital multiple clustered dermatofibroma in a 12-year-old girl. Pediatr Dermatol 2014; 31(1): 105–106. doi: 10.1111/j.1525-1470.2011.01681.x.
Gershtenson PC, Krunic AL, Chen HM. Multiple clustered dermatofibroma: Case report and review of the literature. J Cutan Pathol 2010; 37(9): e42–e45. doi: 10.1111/j.1600-0560.2009.01325.x.
Berbis P, Benderitter T, Perier C, Frey J, Privat Y. Multiple clustered dermatofibromas. Evolution over 20 years. Dermatologica 1988; 177(3): 185–188. doi: 10.1159/000248540.
Shaheen B, Saldanha G, Calonje E, Johnston GA. Multiple clustered dermatofibromas (fibrous histiocytomas): An atypical clinical variant of dermatofibroma. Clin Exp Dermatol 2014; 39(1): 88–90. doi: 10.1111/ced.12200.
Soon SL, Howard AK, Washington CV. Multiple, clustered dermatofibroma: A rare clinical variant of dermatofibroma. J C u t a n M e d S u r g 2 0 0 3; 7(6): 455–457. doi: 10.1177/120347540300700604.
Copyright (c) 2021 Brzezinski P, et al.
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Author(s) shall retain the copyright of their work and grant the Journal/Publisher rights for the first publication with the work concurrently licensed under the Creative Commons Attribution-Noncommercial 4.0 International License
Under this license, author(s) will allow third parties to download, reuse, reprint, modify, distribute and/or copy the content under the condition that the authors are given credit and that the work is not used for commercial purposes. No permission is required from the authors or the publisher.
This broad license intends to facilitate free access, as well as the unrestricted use of original works of all types. This ensures that the published work is freely and openly available in perpetuity.
