Clinical and dermoscopic features of nevi in patients with psoriasis

Natalia Glebovna Ilina; Yulia Mihailovna Krinitsuna; Aleksey Viktorovich Taganov; Andrey Aleksandrovich Tulupov; Irina Stanislavovna Kolesnikova; Dmitry Vladimirovich Yudkin; Irina Gennadievna Sergeeva

doi:10.18282/jsd.v6.i1.50

Natalia Glebovna Ilina Novosibirsk State University
Yulia Mihailovna Krinitsuna Novosibirsk State University Novosibirsk Research Institute of Regional Pathology and Pathomorphology
Aleksey Viktorovich Taganov Scientific Research Centre ‘Clinic of Dermatology’
Andrey Aleksandrovich Tulupov Novosibirsk State University, Medical Department, Vice-Dean, Professor, Doctor of Medical Science The Institute International Tomography Center of the Russian Academy of Sciences, Laboratory of translational brain research, Professor, Doctor of Medical Science
Irina Stanislavovna Kolesnikova Novosibirsk State University, Medical Department, Head of Center of Postgraduate Medical Education, Professor, Doctor of Medical Science The Institute International Tomography Center of the Russian Academy of Sciences, Laboratory of translational brain research, Professor, Doctor of Medical Science
Dmitry Vladimirovich Yudkin Chromosome Pathology Group, Institute of Molecular and Cellular Biology SB Russian Academy of Science, Novosibirsk, Russia
Irina Gennadievna Sergeeva Medical Department, Novosibirsk State University, Novosibirsk, Russia, Laboratory of translational brain research, The Institute International Tomography Center of the Russian Academy of Sciences, Novosibirsk, Russia

DOI: https://doi.org/10.18282/jsd.v6.i1.50

Keywords: melanocytic nevi, psoriasis, dermoscopy, melanoma

Abstract

The aim of the present study is to display the clinical and dermoscopic features of melanocytic nevi of more than 5 mm in diameter in psoriasis patients. A total of 32 patients with psoriasis (21 male, 11 female; average age 37.4) formed the first study group. In 22 patients (68.8%), melanocytic nevi of 5 mm in diameter and bigger (total of 68 nevi) were clinically found. For a randomized trial, 100 people (21 male, 79 female; average age 27.8) without psoriasis were invited to form the second study group. Only 37 of them had nevi ≥5 mm in diameter (total of 60 nevi). Complete questionnaire, full body photometric skin examination, dermoscopy examination on the dermatoscope HEINE MINI 10X with 70% ethyl alcohol immersion, skin type identification according to the Fitzpatrick classification, and nevi assessment according to ABCD and ABC rules were obtained for all recruited people. Our study showed that patients with psoriasis are more susceptible to melanocytic nevi of >5 mm in diameter (68.8%), while the result for the second group was 37%. As for nevi of dysplastic criteria, we found 32% in psoriasis patients vs. 42% in the monitoring group. Moreover, we should bear in mind the influencing factors of skin phototype II and artificial insolation (e.g., tanning, PUVA (Psoralen and ultraviolet A), and narrowband phototherapy 311 nm) obtained by the patients from the first group.

Author Biographies

Natalia Glebovna Ilina, Novosibirsk State University

Medical Department, assistant

Yulia Mihailovna Krinitsuna, Novosibirsk State University Novosibirsk Research Institute of Regional Pathology and Pathomorphology

Medical Department, Head of Skin and Venereal Diseases Training Course, Professor, Doctor of Medical Science

Aleksey Viktorovich Taganov, Scientific Research Centre ‘Clinic of Dermatology’

Professor, Doctor of Medical Science

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