A case report: Staphylococcal scalded skin syndrome in a minor infant
Abstract
Staphylococcal scald skin syndrome is an entity first described by Ritter Von Rittershain in 1878, which was called neonatal exfoliative dermatitis. This situation belongs to a group of pathologies caused by toxins produced by Staphylococcus aureus, called exfoliate A and B, which are characterized by a wide range of segmental lesions and degeneration. It is not a common pathology, but it most often occurs in newborns and children under the age of 5. This study describes a clinical case of a minor baby transferred to the emergency room by his mother, characterized by a systemic rash followed by follicle lesions, which is consistent with the Chikungunya fever (ChikV) outbreak reported in Maracaibo since June 2014.
References
Lowy FD. Staphylococcus aureus infections. N Engl J Med 1998; 339(8): 520–532.
Tuazon CU, Pérez A, Kishaba T, Sheagren JN. Staphylococcus aureus among insulin-injecting diabetic patients: An increased carrier rate. JAMA 1975; 231(12): 1272.
Tuazon CU, Sheagren JN. Increased rate of carriage of Staphylococcus aureus among narcotic addicts. J Infect Dis 1974; 129(6): 725–727.
Von Rittershain RG. Dermatitis of young infants (in Spanish). Zentralzeitung fur Kinderheilkunde 1878; 2: 3.
Li MY, Hua Y, Wei GH, Qiu L. Staphylococcal scalded skin syndrome in neonates: An 8-year retrospective study in a single institution. Pediatr Dermatol 2014; 31(1): 43–7.
Herbst A, Morgan MB. Staphylococcal toxin-mediated scalded skin and toxic shock syndromes. In: Crowe D, Morgan M, Somach S, Trapp K (editors). Deadly dermatologic diseases. Springer; 2016.
Lyell A. The staphylococcal scalded skin syndrome in historical perspective: Emergence of dermopathic strains of Staphylococcus aureus and discovery of the epidermolytic toxin. A review of events up to 1970. J Am Acad Dermatol 1983; 9(2): 285–294.
Handler MZ, Schwartz RA. Staphylococcal scalded skin syndrome: diagnosis and management in children and adults. J Eur Acad Dermatol Venereol 2014; 28(11): 1418–1423.
Amagai M, Matsuyoshi N, Wang ZH, Andl C, Stanley JR. Toxin in bullous impetigo and staphylococcal scalded skin syndrome targets desmoglein 1. Nat Med 2000; 6(11): 1275–1277.
Nikolski PV. K.uchenigu materials on pemphigus foliaceus (in Spanish) [PhD thesis]. Kiev; 1896.
Moss C, Gupta E. The Nikolsky sign in staphylococcal scalded skin syndrome. Arch Dis Child 1998; 79(3): 290.
Hoffmann R, Lohner M, Böhm N, Schaefer H-E, Leititis J. Staphylococcal scalded skin syndrome (SSSS) and consecutive septicaemia in a preterm infant. Pathology - Research and Practice 1994; 190(1): 77–81.
Sethuraman KM, Avabratha KS, Varghese AD, Rai BS. Staphylococcal scalded skin syndrome: A dermatological emergency in pediatrician’s hand. Medical Journal of Dr. D.Y. Patil University 2014; 7(2): 189–191. doi: 10.4103/0975-2870.126336.
Ladhani S, Robbie S, Garratt RC, Chapple DS, Joannou CL, et al. Development and Evaluation of Detection Systems for Staphylococcal Exfoliative Toxin a Responsible for Scalded-Skin Syndrome. Journal of Clinical Microbiology 2001; 39(6): 2050–2054. doi: 10.1128/JCM.39.6.2050-2054.2001.
Sakurai S, Suzuki H, Machida K. Rapid identification by polymerase chain reaction of staphylococcal exfoliative toxin serotype A and B genes. Microbiology and Immunology1995; 39: 379–386. doi: 10.1111/j.1348-0421.1995.tb02216.x.
Nso Roca AP, Baquero-Artigao F, García-Miguel MJ, Benito Caldés C, José Gómez MI de, et al. Neonatal staphylococcal scalded skin syndrome. Acta Pediatr Esp 2007; 65(7): 327–329.
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