Vol. 7 No. 1 (2022)

Full Issue

  • Open Access

    Editorials

    Article ID: 179

    Treatment of keloids: What’s news?

    by Shahin Aghaei

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 1422 Views

    Keloids are still therapeutic glitches, mostly disfiguring lesions which cause physical, functional and psychological burdens. Most patients with keloids are worried about cosmetic, some have grievances of itchy pain or a burning sense around them, though. The firmness can range from pliable to rigid. Most lesions tend to nurture gradually over a few months to a year. Most of them finally discontinue growing and stay unchanging or even withdraw to some extent.

  • Open Access

    Research Highlights

    Article ID: 152

    Analysis of chemokine receptors from angiosarcoma as the potential tumor marker

    by Editorial Office

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 1880 Views

    “Angiosarcoma is a rare malignant skin tumor and appears as a pink-dark red erythema in the frontal region over the forehead in the beginning and it frequently develops in the elderly” described by Tomoo Kishi and his co-authors from Department of Dermatology, Wakayama Medical University, Japan in an original research article published in the Journal of Surgical Dermatology.

  • Open Access

    Original Research Articles

    Article ID: 127

    Expression of chemokine receptors in angiosarcoma

    by Tomoo Kishi, Yuki Yamamoto, Chikako Kaminaka, Seiko Toyozawa, Hiroshi Matsunaka, Fukumi Furukawa

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 2074 Views

    Angiosarcoma is a rapidly progressing malignant skin tumor associated with a poor prognosis. We report an immunohistochemical investigation of chemokine receptors in angiosarcoma. The aim is to investigate chemokine receptor expression and, if it is expressed, to histologically discuss its association with age, sex, development site, and histological type. Analyzed were 12 angiosarcoma samples (mean patient age: 75.7 years old) collected by biopsy or surgery from patients at our department by comparing with 4 granuloma telangiectaticum samples (mean patient age: 37.5 years old) and 16 healthy skin samples as controls. CXCR4, CCR6, CCR7, and SDF-1 expressions were immunohistochemically investigated. CXCR4 expression was positive in 6 of the 12 samples. CCR6 and CCR7 were negative in all samples. SDF-1 was positive in 4 samples. Out of the 6 CXCR4-positive samples, 4 were SDF-1-positive. No significant difference associated with age, sex, development site, or histological type was noted in the expression of CXCR4, CCR6, CCR7, or SDF-1. Although CXCR4 is regarded as an index of tumor aggressiveness of malignant melanoma, it is suggested that chemokine receptors, such as CXCR4, do not serve as useful markers of angiosarcoma.

  • Open Access

    Original Research Articles

    Article ID: 178

    The diagnostic accuracy of the mobile phone teledermatoscopy

    by Hamza Yildiz, Memet Ersan Bilgili, Hasan Aktug Simsek

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 3272 Views

    The positive predictive value (PPV) of smart mobile phone teledermatoscopy is not known. The main purpose of the present study was to investigate the sensitivity and positive predictive values (PPVs) of smart mobile phone teledermatoscopy. Over a period of 6 months, up to three clinical and dermatoscopic images were obtained of 67 skin lesions from 67 patients using a mobile phone camera and standard pocket dermatoscopy device. Out of the 67 patients, 44 were men (65.67%) and 23 were women (34.32%). The mean age of the patients was 39.56 ± 22.19 years (ranging from 18 to 92). The majority of the lesions (71.64%; n=48) were benign, while 11.94% (n=8) of the biopsies were premalignant and 16.41% (n=11) of the lesions were malignant. The sensitivity for the diagnosis of benign, premalignant, and malignant lesions were 93.8%, 100%, and 100%, respectively. PPVs for the diagnosis of benign, premalignant, and malignant lesions were 93.8%, 100%, and 100%, respectively. The sensitivity and PPVs of all lesions were 95.9% and 95.7%. The accuracy of the teledermatoscopic consultation with a mobile phone is very high. We therefore think that it can be a cost effective and useful method in the consultation at distance.

  • Open Access

    Original Research Articles

    Article ID: 168

    Volumetric estimation of autologous fat for augmentation of contour defects of face

    by Shilpi Bhadani, Sujata Sarabahi, Savita Arora, Vinay Kumar Tiwari, Anmol Chugh

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 3360 Views

    Autologous fat transfer for correcting contour defects of face has gained wide popularity in aesthetic surgery. However, quantification of fat requirement and its survival is still a fertile area for research to improve the predictability of volume retention of injected fat. There have been no detailed studies of the calculation for the amount of fat to be injected and percentage of fat retained. The objective of this study was to quantify the amount of fat required for correcting a facial deformity and amount retained postoperatively over a period of 6 months. Thirty patients were recruited in a prospective study where in, the fat requirement for augmenting the soft tissue defect was assessed using USG preoperatively and followed up at 1, 3 and 6 months by the same technique. It was found that USG is a simple, objective, reliable, cost-effective method of assessing the fat requirement and retention in autologous fat transfer.

  • Open Access

    Reviews

    Article ID: 35

    Treatment modalities for hyperpigmented skin lesions: A brief overview

    by Yan Teng Khoo, Ahmad Sukari Halim

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 13421 Views

    Skin hyperpigmentation involves a broad range of skin conditions, including epidermal pigmented lesions, dermal pigmented lesions, and mixed pigmented lesions. Treatment includes various modalities such as brightening cream, chemical peeling, and laser therapy. Responses to various treatment modalities can be quite varied depending on the type of treatment and the degree of pigmentation. Sometimes a lesion can lighten or even partially disappear, while other lesions may recur. This paper provides a brief overview of treatment modalities available for hyperpigmented skin lesions including the importance of photoprotection, various types of brightening creams, suitable types of chemical peels, specific laser therapies targeted for skin hyperpigmentation, and surgery.

  • Open Access

    Reviews

    Article ID: 165

    Fiddler’s neck: Cultural influences modify clinical presentation influences

    by Sundeep Chowdhry, Sameeksha Chand, Paschal D'Souza

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 1737 Views

    Fiddler’s neck which is also referred to as a “violin hickey” is a benign dermatologic occupational disease associated with the use of certain instruments like the violin, viola, cello etc. It is believed to be a type of allergic contact dermatitis, manifesting as an acute or chronic eczematous lesion typically at the submandibular and/or supraclavicular region on the side of neck. It can present as erythema, oedema and/or vesicles in the acute stage and as scaling, lichenification, hyperpigmentation and scarring in the chronic stage. Acne mechanica has also been considered by some authors as a presentation of fiddler’s neck. Occasionally, there may be associated swelling redness or a cystic lesion that makes it difficult to differentiate from lymphedema or a salivary gland tumor. PubMed search for articles about this entity resulting in instrument-induced dermatitis yielded few results of this forgotten entity which mimics a love bite (love hickey). For diagnosis, history of the usage of a string instrument which is held between the shoulder and neck, local physical examination and a positive patch test are pre-requisites. Management of fiddler’s neck includes application of topical mild steroid, emollient, proper instrument handling, neck padding, changing the material and polish of the instrument, and/or reducing the amount of playing time. Surgical intervention is usually not advisable unless cystic or tumorous lesions are the manifesting feature. The authors intend to revisit this entity and report an improvised modality that is being used by these instrumentalists in India which may help in prevention of this condition.

  • Open Access

    Perspectives

    Article ID: 137

    Facial laser surgery

    by Shree Harsh, Surendra B. Patil

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 2664 Views

    Lasers have a number of clinical applications on the face, ranging from aesthetic uses such as the rejuvenation of ageing face to functional ones such as the correction of bleeding vascular malformations. The vast growing uses of lasers on the face emphasises the need to have knowledge of the subject. Though the vast spectrum of lasers is very difficult to compile in an article, the authors give an overview of the application of lasers in the facial region and discuss the most defining treatment of the individual disease processes.

  • Open Access

    Short Communications

    Article ID: 139

    Laser microporation: A promising field in transdermal drug delivery

    by Mozhdeh Sepaskhah

    Journal of Surgical Dermatology, Vol.7, No.1, 2022; 2807 Views

    Topical therapy is an expanding field not only in dermatology but also in other fields of medicine. An expanding list of systemic medications have been applied topically in several dermatologic conditions. Drugs applied topically have the advantage of fewer side effects, and bypassing the first-pass effect. Also, painless drug delivery which is especially encouraging in children, makes transdermal drug delivery even more appealing.