Recurrent verrucous carcinoma of the foot: A case report
Abstract
Verrucous carcinoma is an uncommon, locally invasive and slow growing squamous cell carcinoma of the skin and mucous membrane. The proposed causative agent for verrucous carcinoma is human papillomavirus (HPV). It has low metastatic potential compared to squamous cell carcinoma. This is a report of a 75-year-old male admitted with history of growth over the forefoot. Histopathological examinations confirmed verrucous carcinoma and the patient underwent forefoot amputation with 2 cm clear surgical margin. During the 4th month of follow-up, the patient developed a lesion at the post-operative site which was proven as a recurrence. Even though it carried low metastatic potential, it needed repeated resection or amputation because of high local recurrence.
References
Hassona Y, Scully C. Verrucous tongue lesion. N Engl J Med 2015; 372(21): 2049. doi: 10.1056/NEJMicm1408030.
Alkan A, Bulut E, Gunhan O, Ozden B. Oral verrucous carcinoma: A study of 12 cases. Eur J Dent 2010; 4(2): 202 –207.
Lesic A, Nikolic M, Sopta J, Starcevic B, Bumbasirevic M, et al. Verrucous carcinoma of the foot: A case report. J Or-thop Surg (Hong Kong) 2008; 16(2): 251–253.
Pempinello C, Bova A, Pempinello R, Luise R, Iannaci G. Verrucous carcinoma of the foot with bone invasion: A case report. Case Rep Oncol Med 2013; 2013: e135307. doi: 10.1155/2013/135307.
Samman M, Sethi N. Oral verrucous pre-malignant lesions and HPV. Clin Otolaryngol 2015; 40(3): 292–293. doi: 10.1111/coa.12374.
Santoro A, Pannone G, Contaldo M, Sanguedolce F, Es-posito V, et al. A troubling diagnosis of verrucous squa-mous cell carcinoma (“the bad kind” of keratosis) and the need of clinical and pathological correlations: A review of the literature with a case report. J Skin Cancer 2010; 2011: e370605. doi: 10.1155/2011/370605.
García-Gavín J, González-Vilas D, Rodríguez-Pazos L, Sánchez-Aguilar D, Toribio J. Verrucous carcinoma of the foot affecting the bone: Utility of the computed tomogra-phy scanner. Dermatol Online J 2010; 16(2): 8.
Miller SB, Brandes BA, Mahmarian RR, Durham JR. Verrucous carcinoma of the foot: A review and report of two cases. J Foot Ankle Surg 2001; 40(4): 225–231. doi: 10.1016/S1067-2516(01)80022-3.
Suen K, Wijeratne S, Patrikios J. An unusual case of bilat-eral verrucous carcinoma of the foot (epithelioma cunicu-latum). J Surg Case Rep 2012; 2012(12): 1–3. doi: 10.1093/ jscr/rjs020.
Yoshitatsu S, Takagi T, Ohata C, Kozuka T. Plantar verru-cous carcinoma: Report of a case treated with Boyd ampu-tation followed by reconstruction with a free forearm flap. J Dermatol 2001; 28(4): 226–230. doi: 10.1111/j.1346- 8138.2 001.tb00122.x.
Copyright (c) 2019 Pandiaraja J and Uthayam S
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Author(s) shall retain the copyright of their work and grant the Journal/Publisher rights for the first publication with the work concurrently licensed under the Creative Commons Attribution-Noncommercial 4.0 International License
Under this license, author(s) will allow third parties to download, reuse, reprint, modify, distribute and/or copy the content under the condition that the authors are given credit and that the work is not used for commercial purposes. No permission is required from the authors or the publisher.
This broad license intends to facilitate free access, as well as the unrestricted use of original works of all types. This ensures that the published work is freely and openly available in perpetuity.
