Vol. 7 No. 2 (2022)

Open Access

Original Research Articles

Article ID: 187

Effect of cryotherapy and ALA-PDT therapy on skin cancer

by Zhi Zhong, Hongliu Deng, Wei Liu

Journal of Surgical Dermatology, Vol.7, No.2, 2022; 451 Views

Objective: to study the effect of cryotherapy and ALA-PDT therapy on skin cancer. Methods: this study selected 60 patients with skin cancer admitted to Ankang People’s Hospital of Shaanxi Province from January 2014 to December 2019. According to different treatment methods, 30 patients treated with ALA-PDT were included in the control group, while 30 patients treated with cryotherapy combined with ALA-PDT were included in the observation group. The total effective rate, pain score, surgical trauma area, incidence of adverse reactions and total satisfaction rate of appearance were compared between the two groups. Results: the treatment efficiency of the observation group was 96.7%, which was higher than that of the control group (73.3%), with a statistically significant difference (P < 0.05). The pain score in the observation group was (4.12 ± 1.03), higher than that of the control group (3.45 ± 0.86), and the surgical trauma area was (1.26 ± 0.04) cm², lower than that of the control group (1.39 ± 0.05) cm², with a statistically significant difference (P < 0.05). The difference was statistically significant (all P < 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Besides, the total satisfaction rate of the observation group was 93.3%, which was higher than that of the control group (66.7%), and the difference was statistically significant (P < 0.05). Conclusion: Cryotherapy combined with ALA-PDT therapy are clinically effective in the treatment of skin cancer, with less invasive surgical areas and higher patient satisfaction with appearance. However, the pain score is relatively higher. Therefore, the appropriate treatment can be clinically considered in a comprehensive manner.

Open Access

Original Research Articles

Article ID: 191

Characterization of the elderly with a possible diagnosis of skin cancer

by José Antonio Bordelois Abdo, Mauricio López Mateus, Iliana Fernández Ramírez

Journal of Surgical Dermatology, Vol.7, No.2, 2022; 553 Views

Introduction:In Cuba, the study of skin cancer in the elderly is one of the social demands. Objective: To describe the clinical epidemiological characteristics of patients with a possible diagnosis of SCin the nursing homes “Caridad Jaca” and “San José” in Guantánamo City in 2017. Method:An observational, prospective, and cross-sectional study was conductedin all theelders (n = 256), and to those elders with possible skin cancer (n = 15); the age, sex, place of birth, address, personal medical history, photos of skin types, lesion characteristics, clinical and dermoscopic diagnosis were specified.Results: 5.9% of the elders were diagnosed with skin cancer. It was more common in men (53.4%),people aged from 70 to 79 (53.4%), and people born or lived in urban areas with skin phototype III (40.0%), 100.0% of which are exposed to sunlight, and 86.7% without sun block. Cancers were more frequently foundin the face (66.7%) less than 1 cm in size (46.6%), which have progressed 3 to 4 years (60.0%), and were single lesions (86, 7%) and basal cell carcinomas (46.6%). 80.0% of all the cases showed a clinical-dermoscopic diagnosis correlation. Conclusions: The incidence of skin cancer in the elderly was low. However, more attention is needed to ensure the diagnosis of this disease at its early stage.